Volume 453 Number 7191 pp1-132, 1 May 2008
* News
- Sediment cores reveal Antarctica's warmer past p13
- Warming Antarctic waters begin to cool p15
* News Features
- Stem cells: The 3-billion-dollar question p18
Can a state do what a country cannot, and transform the way stem-cell research is funded?
- Physics: Quantum all the way p22
How does our classical world emerge from the counter intuitive principles of quantum theory? Can we even be sure that the world doesn't 'go quantum' when no one is watching?
* Commentaries
- Science teaching must evolve p31
Evolutionary theory, study and knowledge moved on dramatically in the latter half of the twentieth century, but school teaching, curricula and teacher training are still in the primeval soup era, says Andrew Moore.
* Books Reviews
- Exemplary epidemiology p34
Mark Woolhouse reviews Modeling Infectious Diseases in Humans and Animals
* News and Views
- Climate change: Natural ups and downs p43
The effects of global warming over the coming decades will be modified by shorter-term climate variability. Finding ways to incorporate these variations will give us a better grip on what kind of climate change to expect.
- Quantum physics: The squeeze goes on p45
After 20 years of hard labour, squeezed states — light and matter whose quantum fluctuations have been arduously suppressed below standard levels of quantum noise — are coming of age and are ripe for application.
- Immunology: T cells hang in the balance p46
Equally important as the immune system's function in fighting invaders is its ability to tolerate self. But environmental toxins could shift the equilibrium between these activities one way or the other.
- Networks: Teasing out the missing links p47
Focusing on the hierarchical structure inherent in social and biological networks might provide a smart way to find missing connections that are not revealed in the raw data — which could be useful in a range of contexts.
- Astrophysics: Rays from the dark p48
The origin of the cosmic rays that bombard Earth has troubled physicists for nigh on a century. Supernova remnants are a favoured source — but we should keep our minds open to alternatives
* Articles
- Advancing decadal-scale climate prediction in the North Atlantic sector p84
- Origin of a 'Southern Hemisphere' geochemical signature in the Arctic upper mantle p89
- Genome-wide screen reveals APC-associated RNAs enriched in cell protrusions p115
Volume 452 Number 7190 pp913-1032, 24 April 2008
*News
- Swiss 'dignity' law is threat to plant biology p919
Government ethics committee guidelines could halt techniques such as hybridization of roses.
- Biologists initiate plan to map human proteome p920
Project aims to characterize all human proteins.
Project aims to characterize all human proteins.
* News Features
- Biomedical science: Betting the bank p926
Lyle Palmer has plans for a "ludicrously ambitious" gene–disease research project.
Lyle Palmer has plans for a "ludicrously ambitious" gene–disease research project.
- Atmospheric physics: Heating up the heavens p930
Battling rumours of death beams and mind control, an ionosphere research facility in Alaska finally brings science to the fore.
Battling rumours of death beams and mind control, an ionosphere research facility in Alaska finally brings science to the fore.
* Books Review
- Technological twist on taxonomy p939
Kevin Kelly reviews Systematics as Cyberscience: Computers, Change, and Continuity in Science by Christine Hine.
Kevin Kelly reviews Systematics as Cyberscience: Computers, Change, and Continuity in Science by Christine Hine.
* News and Views
- Optics: Light reined in p942
Light always travels at the same speed in a vacuum, no more, no less. But in materials, there's room for manoeuvre: tweak the right material in the right way, and exciting optoelectronic properties result.
Light always travels at the same speed in a vacuum, no more, no less. But in materials, there's room for manoeuvre: tweak the right material in the right way, and exciting optoelectronic properties result.
- 50 & 100 Years Ago p943
Of the many craters on the Earth known to have been produced by fallen meteors, a few have left no signs of the meteor which caused them, apart from the huge holes created in the Earth's crust. Large meteorite fragments have been found in or near most craters.
- Oceanography: Bottom of the top of the world p945
The floor of the Arctic Ocean comes into sharper focus with the publication of an improved version of a bathymetric chart first released in provisional form in 1999, and as version 1 in 2001. Accurate mapping of the ocean bottom is essential for modelling deep ocean circulation
- Astrophysics: Exhaust inspection p945
What do you see if you peer into the exhaust of a jet engine larger than our Solar System?
What do you see if you peer into the exhaust of a jet engine larger than our Solar System?
- Gene transcription: Two worlds merged p946
Why would two distant genes — on separate chromosomes and from different nuclear locations — unite in response to signals for gene expression?
Why would two distant genes — on separate chromosomes and from different nuclear locations — unite in response to signals for gene expression?
* Articles
-The genome of the model beetle and pest Tribolium castaneum p949
Tribolium castaneum is a member of the most species-rich eukaryotic order, a powerful model organism for the study of generalized insect development, and an important pest of stored agricultural products. We describe its genome sequence here.
- Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA p961
- Mountain pine beetle and forest carbon feedback to climate change p987
- The draft genome of the transgenic tropical fruit tree papaya (Carica papaya Linnaeus) p991
- Upper intestinal lipids trigger a gut–brain–liver axis to regulate glucose production p1012
- Crystal structure of the repressor and a model for pairwise cooperative operator binding p1022
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